Molecular surface of the ABL kinase domain (PDB 1IEP) with imatinib, in orange, seated in its binding pocket; a sparse graph of surface points overlays the protein, with the points lining the pocket highlighted.

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Scanning surface626 surface nodes · 1,426 edges

ABL kinase domain + imatinib, crystal structure PDB 1IEP · sequence UniProt P00519 (ABL1, res. 229–498) · 0/21 pocket residues ≤4 Å · attention sweep is illustrative; pocket and pose are experimental.

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Crystal structure resolution: 2.10 Å
Pocket residues ≤ 4 Å: 21
Weekly digests published: 24
Tracks followed: 3

Latest digest · week to date, cut-off 9 Oct 07:45 UTC

Weekly Intelligence Digest — 5–11 October 2026

Lead item · 01.1Nature Medicine publishes the multicategory MedGemma evaluation: smaller, specialized models are becoming credible medical-imaging research infrastructure.

Radioligand theranostics: Transforming cancer precision

With advances in companion diagnostics, AI-powered dosimetry, and the expansion of new isotopes and cancer targets, we’re entering an era of highly personalized, effective, and scalable oncology treatment.

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